Molecular Upconversion

PhD in Molecular Upconversion Luminescence via [d–f] Hybrids

A fully funded PhD opportunity in cutting-edge molecular upconversion luminescence research, focusing on heteropolymetallic [d–f] hybrids for next-generation bioimaging technologies. Offered by the University of Southampton for UK-only applicants under the Faculty of Engineering and Physical Sciences.

Important Information 

Field Details
Title PhD in Molecular Upconversion Luminescence via [d–f] Hybrids
Organization/Publisher University of Southampton
Work Location Southampton, United Kingdom
Research Field Inorganic Chemistry, Photophysics, Molecular Upconversion, Bioimaging
Funding Info Fully Funded by EPSRC DLA
Application Deadline March 31, 2026
Country United Kingdom
Researcher Profile PhD Student (UK Applicants Only)
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Required Qualification UK 2:1 Honours Degree or International Equivalent
Required Experience Background in Chemistry/Materials/Photophysics preferred
Salary Details Standard UKRI stipend + UK tuition fees for up to 4 years

The University of Southampton invites applications for a fully funded PhD position in Molecular Upconversion Luminescence via [d–f] Hybrids, aimed at pioneering next-generation luminescent systems for advanced bioimaging applications. This project sits within the Faculty of Engineering and Physical Sciences and is ideal for candidates driven to innovate in inorganic chemistry, photophysics, and energy-transfer mechanisms.

About the Project

This PhD focuses on developing heteropolymetallic architectures that combine transition-metal complexes (RuII, IrIII, PtII) with lanthanide centres (YbIII, NdIII). These molecular systems are engineered to enhance two-photon upconversion (UC) luminescence — a transformative technique for medical imaging due to its deep tissue penetration, reduced autofluorescence, and ultra-long phosphorescence lifetimes.

You will conduct multi-step synthesis of target molecular systems, followed by extensive photophysical characterisation using luminescence spectroscopy. The goal is to uncover fundamental energy-transfer processes and develop molecular UC probes with unprecedented efficiency for in vivo use.

Research Training & Facilities

Throughout this PhD, you will gain hands-on expertise in:

  • Synthetic organic and organometallic chemistry

  • Coordination chemistry

  • Photoluminescence spectroscopy

  • Single-crystal X-ray crystallography

  • NMR, IR, HPLC, Mass Spectrometry

  • Advanced X-ray diffraction facilities

You will also participate in seminars, group meetings, and international conferences, with full access to the PGR Development Hub for professional skill-building.

Eligibility Requirements

Applicants must have:

  • A UK 2:1 honours degree or international equivalent

  • Strong background in Chemistry or related fields

  • Interest in inorganic photophysics, luminescence, or molecular imaging

UK-only applicants are eligible for this funding.

Funding

This PhD is fully funded by the EPSRC DLA, covering:

  • Full UK tuition fees

  • Standard UKRI annual stipend

  • Up to 4 years of financial support

How to Apply

To apply:

  1. Choose Programme Type: Research, Academic Year 2026/27, Faculty of Engineering & Physical Sciences

  2. Select full-time or part-time

  3. Search for PhD Chemistry (7189)

  4. Enter the supervisor’s name in section 2

Required documents:

  • Updated CV

  • Two academic references

  • Degree certificates and transcripts

  • English language qualification (if applicable)

For academic enquiries, contact:
Dr Richard Knighton — R.C.Knighton@soton.ac.uk
General queries: feps-pgr-apply@soton.ac.uk

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